Connectivity of PAH signatures to known perturbagens
PAH model:
All
MCT vs Control
SuHx vs Control
Cell type:
All
Alveolar macrophages
AT1 cells
AT2 cells
B cells
CD8 T cells
Ciliated cells
Classical monocytes
Club cells
Conventional dendritic
Endothelial arterial 1
Endothelial arterial 2
Endothelial capillary
Fibroblasts
ILC2
Interstitial macrophages
Mast cells
Mesothelial cells
Naive T cells
Neutrophils
NK cells 1
NK cells 2
Non-classical monocytes
Plasmacytoid dendritic
Proliferating macrophages
Proliferating T cells
Regulatory T cells
Smooth muscle cells
T cells Serpinb6
Perturbation type:
All
CMap Class
Compound
Gene Knockdown
Gene Overexpression