Description

Upload your network data or select from our database

Input Requirements

• Network file (.txt or .csv)
• Format: "HEAD" "TAIL" "WEIGHT" columns
• Optional: Gene set file for analysis

Output

• Validated network data ready for analysis
• Network preview and statistics

Description

Visualize and download any scGRNdb network

Features

• Interactive network visualization
• Node and edge filtering
• Network statistics and metrics
• Download network files and visualizations

Input Requirements

• Choose a network from the database
• Optional: List of genes to search in the network

Output

• Network visualizations
• Network pathway annotations
• Network, module, and pathway files downloads

Description

Annotate your own network with biological pathways and disease gene sets

Input Requirements

• Network file
• Select a minimum and maximum module size
• Choose a species (human or mouse)
• Select one or multiple pathway databases

Analysis Steps

• Network module detection
• Pathway enrichment analysis
• Visualize the network in the Network Browser

Output

• Network modules
• Network annotations
• Enrichment statistics

Description

Identify cell type networks that best model your gene sets

Input Requirements

• Gene set file
• Choose a species (human or mouse)
• Select one or multiple single cell atlases

Analysis Steps

• Identify the cell type GRN modules enriched for your gene sets
• Visualize two cell type GRNs to compare enriched modules
• Run Key Driver Analysis in Mergeomics for each cell type network of interest
• Compare the key driver subnetworks across cell types

Output

• Prioritized cell type networks and their enrichment scores
• Ready-to-run Key Driver Analysis in Mergeomics for key driver subnetworks
• Network Comparison of enriched modules across cell types

Description

Compare two networks for shared and unique mechanisms and annotations

Features

• Combine two networks
• Compare network structures
• Identify shared and unique nodes/edges
• Download combined network visualizations

Output

• Combined network visualization
• Combined network files